词语大全 skeletal defect中文翻譯

Posted 2022-08-23 文

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词语大全 skeletal defect中文翻譯

The protein nucleic acid plexes were identified by autoradiography for 48 h . the psg5heo and igfbp - 6 promoter pcat vectors were transfected into cos - 7 cells with iipofectamin2000 ; these cos - 7 cells where treated with 1 jxm e2 , with lonm tcdd and with both lonm tcdd and 1 jxm e2 , individually ; the cat protein was examined by cat - els a . results : the congenital skeletal defects in fetal rats were induced with 10 - 15ug / kg tcdd or with 100 - 140 mg / kg ra with dosage - dependence effect . the igfbp - 6 mrna in rat calvaria tissue and mc - 3t3 - el cells were increased with tcdd and ( or ) ra , whereas the cell propferation and igf - 2 mrna in mc - 3t3 - el cells was decreased in the status of e2
結果: tcdd在大鼠胚胎發育時期具有骨骼致畸作用，骨骼發育畸形包括:內翻足、脊柱裂、顱面骨發育缺陷、無尾畸形等;隨著tcdd濃度的升高( 10一15林擴kg ) ，致畸率明顯上升( 14 . 7 %一24 . 6 % ) ; tcdd和ra聯合用藥可以增強對大鼠骨骼發育的致畸效應; e :對成骨細胞內igf一2基因有正性調節作用，對igfbp一6基因有負性調節作用， tcdd可以抑制e :對細胞內xgf一2和igfbp一6的調節作用。