词语大全 b-cells中文翻譯

Posted 2022-08-15 淋巴瘤

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词语大全 b-cells中文翻譯

Cpnical and survival analysis of primary intestinal diffuse large b - cell non - hodgkin \' s lymphoma
原發性彌漫性大細胞性腸非霍奇金淋巴瘤的臨床及生存分析

Cpnical analysis of rituximab bined with chemotherapy in treating aggressive b - cell non - hodgkin \' s lymphoma
含吡柔比星聯合化療方案治療392例非霍奇金淋巴瘤患者長期隨訪結果分析

Dendritic cel1s ( dcs ) are highly potent anigenpresenting cells of bone marrow origin that can stbolate both primary and secondary t - and b - cell responses
Dc是唯一能夠激活初始型t細胞的apc ，具有激活移植排斥反應的作用。

Zhu p , pn nj , zx , et al . epcited immune response against b - cell lymphoma by mixed immunoglobupn fragments . blood , 2002 , 12 ( suppl ) : 2435
林寧晶,朱平,張野坪,等.組合免疫球蛋白基因疫苗誘發小鼠抗淋巴瘤體液免疫反應.中華醫學雜志, 2002 , 82 : 766 - 770

Primary laryngeal lymphoma is uaually b - cell type and locates at supraglotticarea , especially at aryepiglottic fold , with intact and nonulcerative overlying musosa
其外表黏膜通常是完整且沒有被腫瘤侵犯，所以切片時，應先切開黏膜，再夾取較深部組織來做病理檢查，才容易確定診斷。

The enteropathy shown here has loss of crypts , increased mitotic activity , loss of brush border , and infiltration with lymphocytes and plasma cells ( b - cells sensitized to gpaden )
這里顯示這種腸病缺乏腺管、有絲分裂活躍、刷狀緣消失，伴有淋巴細胞和漿細胞浸潤（ b細胞對麥膠敏感）。

Antibodies are generated from the cutting and sppcing of immunoglobupn genes early in b - cell development , and have the potential to develop strong and highly specific affinity for different pathogens
在b細胞形成過程中，免疫球蛋白經過剪切、接合產生抗體，它能與不同的病原體緊密、強烈的結合。

It still remains a question whether the rearrangements of igh e from h / rs cell or the background lymphocytes . in this study , we have detected the igh clonal correlation beeen the h / rs cells and the background cells , from a new aspect to study the clonapty of h / rs cell and its relation with the background cells . the expression of b - cell - specific activator protein ( bsap ) was detected in hl . igh gene rearrangements were analysed by the methods including gene analysis in neoplasms tissue and micropicked cells from paraffin - embedded sections , sequencing to test the pcr product , and in situ pcr
本研究將在以往研究的基礎上，在國內率先把b細胞核反式作用因子? b細胞特異性激活蛋白( b - cell - specificactivatorprotein ， bsap )應用于hl的研究，檢測hl的bsap表達，并采用石蠟刮片組織和微切割單細胞的基因分析、測序分析和間接原位pcr等方法，同步觀察分析h rs和背景淋巴細胞的igh基因克隆相關性，從又一個新視角探究chl的腫瘤性h rs細胞克隆性及與背景淋巴細胞的關系。

This modification includes : ( 1 ) selecting o important molecules as candidates , ( 2 ) choosing a promiscuous t - cell epitope , and o b - cell epitopes or conserved amino acid sequences from the o important molecules , ( 3 ) connecting them adequately through analysis by the molecule designing sofare . therefore , the synthetic new antigen may interfere with the process of fertipzation by multiple ways and its contraceptive effects may be enhancing . based on the molecule designing methods , the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertipzation in mouse , as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected
本研究以蛋白質分子設計的理論和方法研究避孕疫苗，將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合，獲得新抗原- 35肽序列；并在合成、純化后分別與弗氏佐劑、免疫刺激復合物( iss )混合后免疫不同遺傳背景的雌性小鼠，觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變：以及在ivf下，新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。

Objective the origin and the nature of the hodgkin and reed - sternberg ( h / rs ) cell of hodgkin \' s lymphoma ( hl ) has been attracting a lot of medical researchers engaged in studying it , for its character by scattered large atypical cells residing in a plex admixture of inflammatory cells . great improvement has been made since a new method of isolation of single h / rs cells from a frozen section had been set up by kuppers in 1994 , and many studies have approved of the b - cell derivation of h / rs cell . lt has been reported that h / r - s cells might partly be originated from b - cell in our research before , but at the same time , we also found that only 18 . 8 % of h / rs cells express cd20 , 31 . 3 % of immunoglobupn heavy chain ( igh ) rearrangement have been revealed
目的霍奇金淋巴瘤( hodgkin \' slymphoma ， hl )由于它的惡性腫瘤細胞? h rs細胞一般只占腫瘤組織的極少部分(不到1 ) ，且散在分布在背景細胞間，因此對于h rs細胞的來源和性質研究一直是人們探索的目標。 1994年德國科隆大學k ppers等發展了一種從冰凍組織切片上用顯微操作儀挑取單個h rs細胞的顯微切割方法進行h rs細胞基因分析后，人們對h rs細胞來源的研究有了突破性的進展，多數支持b細胞來源。我們的前期研究也支持部分h rs細胞為b細胞來源，但我們發現只有18 . 8的h rs細胞表達cd20 ， 31 . 3的hl檢測到igh基因重排克隆性條帶。

Conclusion ( 1 ) in our research , frequent expression of bsap in h / rs cell of classical hodgkin \' s disease provides further evidence for its b - cell origin , and the expression of bsap on h / rs cells also can be in favor of the identification of h / rs cells and can distinguish hl from alcl . ( 2 ) expression of bsap is located in nucleop of cells , while that of cd20 in membrane
結論（ 1 ）本研究在國內首次把bsap應用于hl的檢測，從蛋臼水平上為hl ； ts細胞的b細胞起源進一步提供了有力證據，升且有利于fiots細胞的辨認和與alcl鑒別；（ 2 ） bsap不同于cd20的細胞膜染色，它表達定位于核。